The Nerazzurri claimed a 1-0 win over their Group C rivals last week in the race to join likely table-toppers Bayern Munich in the last-16.
Both sides have lost to the imperious Bayern already, highlighting the importance of this clash at the Camp Nou.
Barcelona come into the game off the back of a 1-0 win over Celta Vigo that kept them above Real Madrid in LaLiga, while leaky Inter beat Sassuolo but are off the pace and seventh in Serie A.
Here are all the details for tuning in…
Where to watch FC Barcelona vs Inter Milan
TV channel: In the UK, the game will be broadcast live on BT Sport 4, with coverage starting at 7.45pm BST ahead of an 8pm kick-off.
Live stream: Subscribers can watch the match live via the BT Sport app or website.