No club has won the FA Cup more often than the Gunners, who have lifted the trophy 14 times.
Clearly, all eyes are on the Premier League but a deep run in the FA Cup would be another major statement of intent from a club on the up.
Here’s everything you need to know.
Date, kick-off time and venue
The FA Cup Third Round game is scheduled for an 8pm GMT kick-off time on Monday January 9, 2023.
The Kassam Stadium in Oxford will host.
Where to watch Oxford vs Arsenal
TV channel: The game will be broadcast on free-to-air TV on ITV 1 and STV.
Live stream: ITVX and the STV Player will both offer live stream services across mobile devices, laptops, games consoles and tablets.
LIVE coverage: Follow all of the action with Standard Sport’s dedicated match blog. Simon Collings will be providing expert analysis from the ground.
Oxford team news
The U’s do not have any fresh injury concerns and do have a recent track record in pulling off cup upsets.
Former Liverpool youngster Cameron Brannagan is a threat, having scored six goals from midfield this season while striker Matty Taylor offers more firepower.
Arsenal team news
Emile Smith Rowe is in contention to feature as the England international faces a late fitness test, having been ruled out of action since before the World Cup.
Matt Turner, Kieran Tierney, Rob Holding and Takehiro Tomiyasu are also expected to start, while Marquinhos, Fabio Vieira, Mohamed Elneny and Albert Sambi Lokonga could feature.
Oxford vs Arsenal prediction
It’s difficult to imagine an Oxford side struggling for consistent form in League One posing the Premier League leaders all too much of a threat.
Arsenal to win 3-0.
Oxford vs Arsenal H2H
Oxford wins: 2
Arsenal wins: 4
Oxford vs Arsenal latest odds
Oxford to win: 16/1
Arsenal to win: 1/7
Odds via Betfair and subject to change.